The study of the effect of drinks based on extracts of herbal adaptogens on the functional status of athletes during physical activity


  • Leyla Martazanova Outpatient Clinic Of Nasyr-Kortsky Administrative District, Yuzhnaya Str., 2, 386140, Nasyr-Kortsky Administrative District, Nazran, Republic Of Ingushetia, Russia, Tel.: +7-905-410-73-36
  • Alina Maslova Stavropol State Medical University, Faculty of Medicine, Department of Therapy, Mira Str., 310, 355017, Stavropol, Russia, Tel.: +7-919-755-39-64
  • Karen Ulikhanov Rostov State Medical University, Faculty of Medicine, Department of Therapy, Nakhichevan Lane, 29, 344022, Rostov-On-Don, Russia, Tel.: +7-905-417-85-72
  • Diana Khadaeva North Ossetian State Medical Academy, Faculty of Medicine, Department of Therapy, Maxim Gorky Str., 83, 362025, Vladikavkaz, Republic of North Ossetia-Alania, Russia, Tel.: +7-905-490-85-55
  • Aminat Shemshedinova Dagestan State Medical University, Faculty of Medicine, Department of Therapy, 5 Gusaeva Str., 367000, Makhachkala, Republic of Dagestan, Russia, Tel.: +7-906-463-29-10
  • Aminat Magomedysupovna Abdullayeva Dagestan State Medical University
  • Diana Makaeva North Ossetian State Medical Academy, Faculty of Medicine, Department of Therapy, Maxim Gorky Str., 83, 362025, Vladikavkaz, Republic of North Ossetia-Alania, Russia, Tel.: +7-918-747-65-66
  • Rayana Abdulvakhayova North Ossetian State Medical Academy, Faculty of Medicine, Department of Therapy, Maxim Gorky Str., 83, 362025, Vladikavkaz, Republic of North Ossetia-Alania, Russia, Tel.: +7-918-746-77-08
  • Amina Ozdoeva Rostov State Medical University, Faculty of Medicine, Department of Therapy , Nakhichevan Lane, 29, 344022, Rostov-On-Don , Russia, Tel.: +7-918-798-11-54
  • Sergey Povetkin North Caucasus Federal University, Faculty of Food Engineering and Biotechnology, Department of Food Technology and Engineering Pushkina Street, 1, 355009, Stavropol, Russia, Tel.: +79183500889



herbal extract, adaptogen, sport, adaptive potential


Adverse environmental factors, stress, lack of sleep and rest, and heavy physical exertion, deplete the human body. In particular, the reserves of the main metabolites, water, and oxygen, are very limited. People, especially athletes, need to take special dietary supplements with adaptogenic properties to adapt to stressful extreme loads. In this study, the influence of using extracts of leuzea, ginseng, and Eleutherococcus on athletes' performance, endurance, strength, and emotional state is carried out. The studies were conducted on four groups of male athletes aged from 19 to 25 years. For three weeks, diagnostics of vital lung capacity, Stange, and Genchi tests are carried out, and data on the general impressions of athletes are collected. According to the research results, the use of adaptogens leads to an increase in physical performance. After the first week of the study, a positive effect on the human body are noticed: improve well-being and increased athletic performance. When using Eleutherococcus, there was a change in the work of the central nervous system (motor functions): tasks begin to be performed in an organized and accelerated manner without deterioration of well-being, but the volume of strength exercises remained the same. When using the drug leuzea, muscle strength was noted, which allowed to increase the load. There is a positive effect of phytopreparations on the body, namely on the functions of the cardiovascular, central nervous and endocrine systems. In 4 participants who took leuzea, the performance in power competitions improved by 18.5% compared to the control group. The intake of Eleutherococcus and ginseng is accompanied by an increase in the activity of neurotransmitter cells, i.e., the effect on the mesolimbic system.  In addition, a study of hematological blood parameters and hormonal statuses at the beginning and end of the study was conducted with the subjects who took leuzea extract. So, the use of the drug leuzea leads to the following positive changes: a more significant increase in ESR, a more significant increase in hemoglobin, compared with the control group. The conclusion is made about the practicality of taking biologically active additives based on some plant adaptogens.


Download data is not yet available.


Metrics Loading ...


Gasta, M. (2020). The Nutrition Assessment of Metabolic and Nutritional Balance. In Integrative and Functional Medical Nutrition Therapy (pp. 99–122). Springer International Publishing. DOI:

Latkov, N., Vekovtsev, A., Koshelev, Y., & Bakaytis, V. (2015). Relevant problems of sports nutrition. In Foods and Raw Materials (Vol. 3, Issue 1, pp. 77–85). Kemerovo State University. DOI:

Belyaev, N. G., Rzhepakovsky, I. V., Timchenko, L. D., Areshidze, D. A., Simonov, A. N., Nagdalian, A. A., Rodin, I. A., Rodin, M. I., Povetkin, S. N., & Kopchekchi, M. E. (2019). Effect of training on femur mineral density of rats. In Biochemical and Cellular Archives (Vol.19, Issue 2, pp. 3549–3552). DR. P. R. YADAV.

Chappell, A. J., Simper, T., & Barker, M. E. (2018). Nutritional strategies of high level natural bodybuilders during competition preparation. In Journal of the International Society of Sports Nutrition (Vol. 15, Issue 1). Informa UK Limited. DOI:

Barybina, I. L., Beloysova, V. E., Voblikova, V. T., Simonov, N. A., & Ziruk, V. I. (2019). Multicomponent meat products for sports nutrition. In Journal of Hygienic Engineering and Design (Vol. 28, pp. 81–84). Consulting and Training Center – KEY.

Gutnova, T. S., Kompantsev, D. V., Gvozdenko, A. A., Kramarenko, V. N., & Blinov, A. V. (2021). Vitamin d nanocapsulation. In izvestiya vysshikh uchebnykh zavedenii khimiya khimicheskaya tekhnologiya (Vol. 64, Issue 5, pp. 98–105). Ivanovo State University of Chemistry and Technology. DOI:

Siddiqui, S. A., Bahmid, N. A., Taha, A., Abdel-Moneim, A.-M. E., Shehata, A. M., Tan, C., Kharazmi, M. S., Li, Y., Assadpour, E., Castro-Muñoz, R., & Jafari, S. M. (2022). Bioactive-loaded nanodelivery systems for the feed and drugs of livestock; purposes, techniques and applications. In Advances in Colloid and Interface Science (Vol. 308, p. 102772). Elsevier BV. DOI:

Panossian, A., & Wagner, H. (2005). Stimulating effect of adaptogens: an overview with particular reference to their efficacy following single dose administration. In Phytotherapy Research (Vol. 19, Issue 10, pp. 819–838). Wiley. DOI:

Nagdalyan, A. A., Oboturova, N. P., Povetkin, S. N., Ziruk, I. V., Egunova, A., Simonov, A. N., Svetlakova, E.V., & Trushov, P. A. (2018). Adaptogens instead restricted drugs research for an alternative items to doping in sport. In Research Journal of Pharmaceutical, Biological and Chemical Sciences (Vol. 9, pp. 1111–1116). RJPBCS.

Panossian, A. (2017). Understanding adaptogenic activity: specificity of the pharmacological action of adaptogens and other phytochemicals. In Annals of the New York Academy of Sciences (Vol. 1401, Issue 1, pp. 49–64). Wiley. DOI:

Panossian, A., Wikman, G., & Wagner, H. (1999). Plant adaptogens III. Earlier and more recent aspects and concepts on their mode of action. In Phytomedicine (Vol. 6, Issue 4, pp. 287–300). Elsevier BV. DOI:

Gerontakos, S., Casteleijn, D., & Wardle, J. (2021). Clinician perspectives and understanding of the adaptogenic concept: A focus group study with Naturopaths and Western Herbalists. In Integrative Medicine Research (Vol. 10, Issue 1, p. 100433). Elsevier BV. DOI:

Kotsoeva, G. A., Esiev, R. K., Toboev, G. V., Zakaeva, R. S., Kulova, A. A., Tsokova, L. V., & Dzagurova, L. A. (2021). Phytoadaptogenic Cocktail Use “Biorithm-E” In The Complex Treatment Of Odontogenic Inflammatory Diseases Of The Maxillofacial Region. In Annals of Dental Specialty (Vol. 9, Issue 2, pp. 52–57). Polaris. DOI:

Sarkar, T., Salauddin, M., Roy, S., Chakraborty, R., Rebezov, M., Shariati, M. A., Thiruvengadam, M., & Rengasamy, K. R. R. (2022). Underutilized green leafy vegetables: frontier in fortified food development and nutrition. In Critical Reviews in Food Science and Nutrition (pp. 1–55). Informa UK Limited. DOI:

Shariati, M. A., Zakabunina, E., Ermolaev, V., Ilmushkin, A., Sepiashvili, E., Simonova, V., Okhramenko, S., Ponomareva, L., Bratishko, N., Maksyutov, R., Melnikova, E., Konovalov, V., Klimov, V., & Ntsefong, G. N. (2021). Review of herbal medicine as a natural gift and proper rifle to overcome pathogenic infections. In Journal of microbiology, biotechnology and food sciences (Vol. 10, Issue 6, p. e4840). Slovak University of Agriculture in Nitra. DOI:

Ayivi, R., Ibrahim, S., Colleran, H., Silva, R., Williams, L., Galanakis, C., Fidan, H., Tomovska, J., & Siddiqui, S. A. (2021). COVID-19: human immune response and the influence of food ingredients and active compounds. In Bioactive Compounds in Health and Disease (Vol. 4, Issue 6, p. 100). Functional Food Center. DOI:

Elmakaoui, A., Bourais, I., Oubihi, A., Nassif, A., Bezhinar, T., Shariati, M. A., Blinov, A. V., Hleba, L., & Hajjaji, S. E. (2022). Chemical composition and antibacterial activity of essential oil of Lavandula Multifida. In Journal of microbiology, biotechnology and food sciences (Vol. 11, Issue 6, p. e7559). Slovak University of Agriculture in Nitra. DOI:

Todorova, V., Ivanov, K., Delattre, C., Nalbantova, V., Karcheva-Bahchevanska, D., & Ivanova, S. (2021). Plant Adaptogens—History and Future Perspectives. In Nutrients (Vol. 13, Issue 8, p. 2861). MDPI AG. DOI:

Liao, L., He, Y., Li, L., Meng, H., Dong, Y., Yi, F., & Xiao, P. (2018). A preliminary review of studies on adaptogens: comparison of their bioactivity in TCM with that of ginseng-like herbs used worldwide. In Chinese Medicine (Vol. 13, Issue 1). Springer Science and Business Media LLC. DOI:

Rzhepakovsky, I. V., Areshidze, D. A., Avanesyan, S. S., Grimm, W. D., Filatova, N. V., Kalinin, A. V., Kochergin, S. G., Kozlova, M. A., Kurchenko, V. P., Sizonenko, M. N., Terentiev, A. A., Timchenko, L. D., Trigub, M. M., Nagdalian, A. A., & Piskov, S. I. (2022). Phytochemical Characterization, Antioxidant Activity, and Cytotoxicity of Methanolic Leaf Extract of Chlorophytum Comosum (Green Type) (Thunb.) Jacq. In Molecules (Vol. 27, Issue 3, p. 762). MDPI AG. DOI:

Karpman, V. L., Belotserkovskii, Z. B., & Gudkov, I. A. (1988). Testing in sports medicine. Fizkultura i sport, Moscow, 208 p. (In Russian)

Karvonen, J., & Vuorimaa, T. (1988). Heart Rate and Exercise Intensity During Sports Activities. In Sports Medicine (Vol. 5, Issue 5, pp. 303–312). Springer Science and Business Media LLC. DOI:

Esmaealzadeh, N., Iranpanah, A., Sarris, J., & Rahimi, R. (2022). A literature review of the studies concerning selected plant-derived adaptogens and their general function in body with a focus on animal studies. In Phytomedicine (Vol. 105, p. 154354). Elsevier BV. DOI:

Sidorova, Y. S., Shipelin, V. A., Petrov, N. A., Zorin, S. N., & Mazo, V. K. (2021). Adaptogenic Properties of a Phytoecdysteroid-Rich Extract from the Leaves of Spinacia oleracea L. In Plants (Vol. 10, Issue 12, p. 2555). MDPI AG. DOI:

Thakur, A. K., Chatterjee, S. S., & Kumar, V. (2015). Adaptogenic potential of andrographolide: An active principle of the king of bitters (Andrographis paniculata). In Journal of Traditional and Complementary Medicine (Vol. 5, Issue 1, pp. 42–50). Elsevier BV. DOI:

Wiegant, F. A. C., Surinova, S., Ytsma, E., Langelaar-Makkinje, M., Wikman, G., & Post, J. A. (2008). Plant adaptogens increase lifespan and stress resistance in C. elegans. In Biogerontology (Vol. 10, Issue 1, pp. 27–42). Springer Science and Business Media LLC. DOI:

Cardoso, C. G., Jr, Gomides, R. S., Queiroz, A. C. C., Pinto, L. G., Lobo, F. da S., Tinucci, T., Mion, D., Jr, & de Moraes Forjaz, C. L. (2010). Acute and Chronic Effects of Aerobic and Resistance Exercise on Ambulatory Blood Pressure. In Clinics (Vol. 65, Issue 3, pp. 317–325). Elsevier BV. DOI:

Shin, Y.-S., Yang, S.-M., Kim, M.-Y., Lee, L.-K., Park, B.-S., Lee, W.-D., Noh, J.-W., Kim, J.-H., Lee, J.-U., Kwak, T.-Y., Lee, T.-H., Park, J., & Kim, J. (2016). Differences in respirogram phase between taekwondo poomsae athletes and nonathletes. In Journal of Physical Therapy Science (Vol. 28, Issue 9, pp. 2495–2500). Society of Physical Therapy Science. DOI:

Schoenfeld, B. J. (2013). Potential Mechanisms for a Role of Metabolic Stress in Hypertrophic Adaptations to Resistance Training. In Sports Medicine (Vol. 43, Issue 3, pp. 179–194). Springer Science and Business Media LLC. DOI:

Kachur, K., & Suntres, Z. E. (2015). The antimicrobial properties of ginseng and ginseng extracts. In Expert Review of Anti-infective Therapy (Vol. 14, Issue 1, pp. 81–94). Informa UK Limited. DOI:

Al-Dujaili, E. A. S., Hajleh, M. N. A., & Chalmers, R. (2020). Effects of Ginseng Ingestion on Salivary Testosterone and DHEA Levels in Healthy Females: An Exploratory Study. In Nutrients (Vol. 12, Issue 6, p. 1582). MDPI AG. DOI:

Medon, P. J., Ferguson, P. W., & Watson, C. F. (1984). Effects of Eleutherococcus senticosus extracts on hexobarbital metabolism in vivo and in vitro. In Journal of Ethnopharmacology (Vol. 10, Issue 2, pp. 235–241). Elsevier BV. DOI:

Panossian, A., & Wikman, G. (2009). Evidence-Based Efficacy of Adaptogens in Fatigue, and Molecular Mechanisms Related to their Stress-Protective Activity. In Current Clinical Pharmacology (Vol. 4, Issue 3, pp. 198–219). Bentham Science Publishers Ltd. DOI:

Vitale, K., & Getzin, A. (2019). Nutrition and Supplement Update for the Endurance Athlete: Review and Recommendations. In Nutrients (Vol. 11, Issue 6, p. 1289). MDPI AG. DOI:

Azmathulla, S., Hule, A., & Naik, S. R. (2006). Evaluation of adaptogenic activity profile of herbal preparation. In Indian Journal of Experimental Biology (Vol. 44, Issue 7, pp. 574–579). National Institute of Science Communication.

Kubo, K., Ikebukuro, T., & Yata, H. (2019). Effects of squat training with different depths on lower limb muscle volumes. In European Journal of Applied Physiology (Vol. 119, Issue 9, pp. 1933–1942). Springer Science and Business Media LLC. DOI:

Wankhede, S., Langade, D., Joshi, K., Sinha, S. R., & Bhattacharyya, S. (2015). Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial. In Journal of the International Society of Sports Nutrition (Vol. 12, Issue 1). Informa UK Limited. DOI:

Greene, E. S., Maynard, C., Owens, C. M., Meullenet, J.-F., & Dridi, S. (2021). Effects of Herbal Adaptogen Feed-Additive on Growth Performance, Carcass Parameters, and Muscle Amino Acid Profile in Heat-Stressed Modern Broilers. In Frontiers in Physiology (Vol. 12). Frontiers Media SA. DOI:

Paraiso, L. F., Gonçalves-e-Oliveira, A. F. M., Cunha, L. M., de Almeida Neto, O. P., Pacheco, A. G., Araújo, K. B. G., Garrote-Filho, M. da S., Bernardino Neto, M., & Penha-Silva, N. (2017). Effects of acute and chronic exercise on the osmotic stability of erythrocyte membrane of competitive swimmers. In D. Laver (Ed.), PLOS ONE (Vol. 12, Issue 2, p. e0171318). Public Library of Science (PLoS). DOI:

Krüger-Genge, A., Sternitzky, R., Pindur, G., Rampling, M., Franke, R. P., & Jung, F. (2019). Erythrocyte aggregation in relation to plasma proteins and lipids. In Journal of Cellular Biotechnology (Vol. 5, Issue 1, pp. 65–70). IOS Press. DOI:

Clerc, F., Reiding, K. R., Jansen, B. C., Kammeijer, G. S. M., Bondt, A., & Wuhrer, M. (2015). Human plasma protein N-glycosylation. In Glycoconjugate Journal (Vol. 33, Issue 3, pp. 309–343). Springer Science and Business Media LLC. DOI:

Filkova, A. A., Martyanov, A. A., Garzon Dasgupta, A. K., Panteleev, M. A., & Sveshnikova, A. N. (2019). Quantitative dynamics of reversible platelet aggregation: mathematical modelling and experiments. In Scientific Reports (Vol. 9, Issue 1). Springer Science and Business Media LLC. DOI:

Rzhepakovsky, I., Siddiqui, S.A., Avanesyan, S., Benlidayi, M., Dhingra, K., Dolgalev, A., Enukashvily, N., Fritsch, T., Heinz, V., Kochergin, S., Nagdalian, A., Sizonenko, M., Timchenko, L., Vukovic, M., Piskov, S., & Grimm, W. (2021). Anti‐arthritic effect of chicken embryo tissue hydrolyzate against adjuvant arthritis in rats (X‐ray microtomographic and histopathological analysis). In Food Science & Nutrition (Vol. 9, Issue 10, pp. 5648–5669). Wiley. DOI:

Nader, E., Skinner, S., Romana, M., Fort, R., Lemonne, N., Guillot, N., Gauthier, A., Antoine-Jonville, S., Renoux, C., Hardy-Dessources, M.-D., Stauffer, E., Joly, P., Bertrand, Y., & Connes, P. (2019). Blood Rheology: Key Parameters, Impact on Blood Flow, Role in Sickle Cell Disease and Effects of Exercise. In Frontiers in Physiology (Vol. 10). Frontiers Media SA. DOI:

Revin, V. V., Ushakova, A. A., Gromova, N. V., Balykova, L. A., Revina, E. S., Stolyarova, V. V., Stolbova, T. A., Solomadin, I. N., Tychkov, A. Yu., Revina, N. V., & Imarova, O. G. (2017). Study of Erythrocyte Indices, Erythrocyte Morphometric Indicators, and Oxygen-Binding Properties of Hemoglobin Hematoporphyrin Patients with Cardiovascular Diseases. In Advances in Hematology (Vol. 2017, pp. 1–9). Hindawi Limited. DOI:

Kraemer, W. J., Ratamess, N. A., Hymer, W. C., Nindl, B. C., & Fragala, M. S. (2020). Growth Hormone(s), Testosterone, Insulin-Like Growth Factors, and Cortisol: Roles and Integration for Cellular Development and Growth With Exercise. In Frontiers in Endocrinology (Vol. 11). Frontiers Media SA. DOI:

Casto, K. V., & Edwards, D. A. (2016). Testosterone, cortisol, and human competition. In Hormones and Behavior (Vol. 82, pp. 21–37). Elsevier BV. DOI:




How to Cite

Martazanova, L., Maslova, A., Ulikhanov, K., Khadaeva, D., Shemshedinova, A., Abdullayeva, A. M., Makaeva, D., Abdulvakhayova, R., Ozdoeva, A., & Povetkin, S. (2023). The study of the effect of drinks based on extracts of herbal adaptogens on the functional status of athletes during physical activity. Potravinarstvo Slovak Journal of Food Sciences, 17, 30–42.

Most read articles by the same author(s)