Nutrigenomics analyze of expression of extracellular leptin receptor by the following essential oil monitoring at the avian models
DOI:
https://doi.org/10.5219/128Keywords:
leptin receptor, gene expression, bird, hormone, essential oilAbstract
Leptin gene was identified in 1994 by positional cloning. His mutation is considered extreme obesity surface phenotype and infertility in ob/ob mice. Most of the research, which followed the discovery of this hormone, focused on the role of leptin in regulating body weight, in order to clarify the pathophysiology of obesity. Many research results show that leptin is not only important in regulating food intake and energy balance, but also performs functions such as metabolic and neuroendocrine hormone. Using herbs and essential oils depends on their antimicrobial activity. Most plants have favorable multifunctional properties, which are the specific content of bioactive components. Some authors characterize fytogénne substance such as natural substancese plant origin, which leave no residues in animal products and is not necessary to keep the trade period before slaughter animals. Analyses suggest that the structural function of the receptor exists as a dimer constructively in the plasma membrane. Each receptor dimer pair is reversibly bound to one molecule of leptin. When bound, signaling pathways are responsible for beginning the activation receptor associated Janus kinase 2 (JAK2) and tyrosine phosphorylation of two key residues in the intracellular part of receptor.
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ANGELOVIČOVÁ, M., MELLEN, M., ANGELOVIČ, M. 2005. Použitie pamajoránovej silice ako náhrady za antibiotikum vo výžive výkrmových kurčiat. In Dni výživy. SPU : Nitra, 2005, p. 1-5. ISBN 80-8069-530- X.
ANGELOVIČOVÁ, M., MELLEN, M., ANGELOVIČ, M. 2005. Uplatnenie biotechnologického postupu náhrady kŕmneho antibiotika premixom škoricovej silice vo výžive výkrmových kurčiat. In Biotechnológie 2006. JU: České Budejovice, 2006, p. 134-136. ISBN 8085-645-53-X.
ASHWELL, C. M., CZERWINSKI, S. M., BROCHT, D. M., 1999. Hormonal regulation of leptin expression in broiler chickens. In Am. J. Physiol., vol. 8., 1999, no. 5, p. 226-232. DOI: https://doi.org/10.1152/ajpregu.1999.276.1.R226
PMid:9887199
BAHRENBERG, G., BERMANN, I., BARTHEL, A., HEKERMAN, P., HEINRICH, P. C., JOOST, H. G., BECKER, W. 2002. Identification of the critical sequence elements in the cytoplasmic domain of leptin receptor isoforms required for Janus kinase/signal transducer and activator of transcription activation by receptor heterodimers. In Mol. Endocrinol., vol. 16., 2002, no. 12, p. 859-72. DOI: https://doi.org/10.1210/mend.16.4.0800
https://doi.org/10.1210/me.16.4.859 DOI: https://doi.org/10.1210/me.16.4.859
PMid:11923481
BANKS, S., DAVIS, M., BATES, S. H., MYERS, M. G. Jr. 2000. Activation of downstream signals by the long form of the leptin receptor. In J. Biol. Chem., vol. 275, 2000, no. 46, p. 14563-14572.
https://doi.org/10.1074/jbc.275.19.14563 DOI: https://doi.org/10.1074/jbc.275.19.14563
PMid:10799542
BULLA, J. 2003. Research and Perspectives of the Modern Biotechnologies. In Animal Husbandry. Život. Prostr., vol. 37, 2003, no. 2, p. 14-16.
CASSY, S., METAYER, S., CROCHET, S., RIDEAU, N., COLLIN, A., TESSERAUD, S. 2004. Leptin receptor in the chicken ovary: potential involvement in ovarian dysfunction of ad libitum-fed broiler breeder hens. In Reproductive Biology and Endocrinology, vol. 2, 2005, no. 72, p. 178-186.
https://doi.org/10.1186/1477-7827-2-72 DOI: https://doi.org/10.1186/1477-7827-2-72
PMid:15473907
DEMETEROVÁ, M. 2004. Súčasné trendy vo výžive hydiny. In Slovenský veterinársky časopis, vol. 29, 2004, no. 5, p. 38-40.
DRDÁK, M., STUDENICKÝ, J., MÓROVÁ, E., KAROVIČOVÁ, J. 1996. Základy potravinárskych technológií. Bratislava, MC, 1996, p. 512.
DRIDI, S., RAVER, N., GUSSAKOVSKY, E. E., DEROUET, M., PICARD, M., GERTLER, A., TAOUIS, M. 2000. Biological activities of recombinant chicken leptin C4S analog compared with unmodified leptins. In Am. J. Physiol., vol. 279, 2000, no. 1, p. 116-123. DOI: https://doi.org/10.1152/ajpendo.2000.279.1.E116
PMid:10893330
EISENBERG, A., BIENER, E., ChARLIER, M., KRISHAN, R. V., DJIANE, J., HERMAN, B., GERTLER, A. 2004. Transacfivation of erb B2 by short and long isoforms of leptin receptors. In FEBSLell., vol. 565, 2004, no. 5, p. 139-142.
https://doi.org/10.1016/j.febslet.2004.03.089 DOI: https://doi.org/10.1016/j.febslet.2004.03.089
PMid:15135067
HEKERMAN, P., ZEIDLER, J., BAMBERG-LEMPER, S., KNOBELSPIES, H., LAVENS, D., TAVEMIER, J., JOOST, H. G., BECKER, W. 2005. Pleiotropy of leptin receptor signalling is defined by distinct roles of the intracellular tyrosines. In J. Febs. J., vol. 272, 2005, no. 8, p. 109-119.
https://doi.org/10.1111/j.1432-1033.2004.04391.x DOI: https://doi.org/10.1111/j.1432-1033.2004.04391.x
PMid:15634336
KAMEL, C., McKAY, R. 2003. Plant extracts enhance performance in broilers under Clostridium perfingers challenge. In J. Anim. Sci., vol. 81, 2003, no. 1, p. 103.
LIU, X., DUNN, J. C., SHARP, P. J., BOSWELL, T. 2006. Molecular cloning snd tissue distribution of a short form chicken leptin receptor mRNA. In Domestic Anim. Endokrinology, vol. 32, 2007, p. 155-166.
https://doi.org/10.1016/j.domaniend.2006.02.001 DOI: https://doi.org/10.1016/j.domaniend.2006.02.001
PMid:16531001
MUDROŇOVÁ, D., NEMCOVÁ, R., GANCARČÍKOVÁ, S., JONECOVÁ, Z., BOMBA, A. 2005. Alternatíva antibiotík v odchove mláďat HZ. In Slovenský chov, vol. 11, 2005, no. 1, p. 33-35.
OPLETĽ, L. 2006. Performing nature – aplikovaná príroda. In Slovenský chov, vol. 11, 2006, no. 6, p. 44.
TAOUIS, M., CHEN, J.W., DAVIAUD, C. 1998. Cloning the chicken leptin gene. In Gene, vol.65, 1998, no. 2, p. 239-242.
https://doi.org/10.1016/S0378-1119(97)00670-7 DOI: https://doi.org/10.1016/S0378-1119(97)00670-7
PMid:9524275
ZHANG, Y., PROENCA, R., MAFFEI, M., BARONE, M., LEOPOLD, L., FRIEDMAN, J. M. 1994. Positional cloning of the mouse obesegene and its human homologue. In Nature., vol. 372, 1994, no. 13, p. 425-432.
https://doi.org/10.1038/372425a0 DOI: https://doi.org/10.1038/372425a0
PMid:798423
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